energy storage cell transplantation
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Preservation media, durations and cell concentrations of short …
Comprehensive evaluation is needed to reflect real cell status before transplantation. Our results show that ADSCs suspended in ME + HSA, at a concentration of 5 × 10 6 cells/ml could be stored for 24 h at 2∼8 °C, which
Aprende másMitochondrial transfer/transplantation: an emerging ...
The transfer/transplantation of mitochondria between cells is equivalent to installing new batteries in cells to supplement ATP production to support the survival of cells with impaired energy metabolism. At present, many experiments have tested the effect of mitochondrial transfer on the bioenergetic levels of ATP in recipient cells in vitro.
Aprende másFrontiers | Biomaterial-Based Schwann Cell Transplantation and …
However, direct cell transplantation often leads to low efficacy, due to injection induced cell damage and rapid loss in the circulatory system. In recent years, biomaterials have received great attention as functional carriers for effective cell transplantation. ... and energy storage of living organisms in animals and plants. For …
Aprende másOptimal Stem Cell Transporting Conditions to Maintain Cell …
We optimized the cell transporting medium, temperature, time, density, and container, and then compared maintenance of stem cell characteristics and inhibition of spontaneous differentiation of the transported cells against the freshly prepared cells.
Aprende másAttenuation of resting energy expenditure following …
Children undergoing hematopoietic stem cell transplantation (HSCT) typically receive parenteral nutrition (PN) due to gastrointestinal toxicities. Accurate determination of …
Aprende másCombination of low-energy shock-wave therapy and bone …
Stem cell transplantation and low-energy shock-wave therapy (LESWT) have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. ...
Aprende másUmbilical cord blood banking for unrelated transplantation: evaluation of cell separation and storage methods
Cost-efficient umbilical cord blood (UCB) banking requires well-standardized methods of volume reduction and storage. To compare UCB fractionation using a technique of hydroxyethyl starch (HES) sedimentation with the Ficoll (double) and Percoll methods, 50 whole units was allocated randomly to each …
Aprende másTrimming the fat: obesity and hematopoietic cell transplantation
Obesity, increasing worldwide, is common in patients undergoing hematopoietic cell transplantation (HCT). This complex physiological state may alter …
Aprende másGuidelines for the collection, processing and storage of human bone marrow and peripheral stem cells for transplantation …
It enumerates how quality control and assurance can be applied to this area of transfusion medicine; procedural steps relating to bone marrow harvest on peripheral blood stem cell collection are outlined and recommended doses of nucleated cells suggested for both procedures. SUMMARY. There are no current U.K. or international …
Aprende másTotal Body Irradiation for Hematopoietic Stem Cell Transplantation ...
Total body irradiation (TBI), used as part of the conditioning regimen prior to allogeneic and autologous hematopoietic cell transplantation, is the delivery of a relatively homogeneous dose of radiation to the entire body. TBI has a dual role, being cytotoxic and immunosuppressive. This allows it to eliminate disease and create "space" …
Aprende másCells | Free Full-Text | Prospects and Potential for Chimerism …
Chimerism analysis after allogeneic hematopoietic stem cell transplantation serves to confirm engraftment, indicate relapse of hematologic malignancy, and attribute graft failure to either immune rejection or poor graft function. Short tandem repeat PCR (STR-PCR) is the prevailing method, followed by quantitative real-time PCR …
Aprende másStrength Training Following Hematopoietic Stem Cell Transplantation
High-dose chemotherapy followed by hematopoietic stem cell transplantation is a potentially curative treatment for a variety of hematologic malignancies, such as acute myeloid leukemia and lymphoma. 1 This intensive cancer therapy, however, is associated with significant acute complications, such as serious infections and graft …
Aprende másGut microbiota and hematopoietic stem cell transplantation: where do we stand? | Bone Marrow Transplantation …
Particularly, GM is involved in energy harvest and storage, and in metabolic functions, 4 limits the access of enteropathogens to the gastrointestinal tract 5 and influences host immunity, being ...
Aprende másElectrospun Nanofiber Membrane for Cultured Corneal Endothelial Cell …
The corneal endothelium, comprising densely packed corneal endothelial cells (CECs) adhering to Descemet''s membrane (DM), plays a critical role in maintaining corneal transparency by regulating water and ion movement. CECs have limited regenerative capacity within the body, and globally, there is a shortage of donor corneas …
Aprende másThe Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage ...
Hydrogen-attenuated inflammatory response in a PMVECs lung transplantation model during cold storage. The effect may be achieved by inhibition of p38 MAPK and NF-κB pathways. Background: Lung ischemia-reperfusion injury (LIRI) remains an important factor for the early mortality of lung transplantations. ...
Aprende másJournal of Energy Storage | ScienceDirect by Elsevier
The Journal of Energy Storage focusses on all aspects of energy storage, in particular systems integration, electric grid integration, modelling and analysis, novel energy storage technologies, sizing and management strategies, business models for operation of storage systems and energy storage …. View full aims & scope.
Aprende másEfficacy of chimeric antigen receptor T cell therapy and autologous stem cell transplant in relapsed or refractory diffuse large B-cell …
Although CAR-T cell therapy showed a beneficial ORR, auto-HSCT exhibited a better long-term treatment superiority in R/R DLBCL patients. Survival outcomes were consistent across different subgroups. Affiliations 1 Department of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for …
Aprende másStem Cells Storage, Packaging, and Transportation
Stem cell storage occurs frequently over the formulation of a cell therapy, from the initial donor cell through the manufacturing process ultimately …
Aprende másCells | Free Full-Text | Immuno-Hematologic Complexity of ABO
ABO incompatibility is not considered a contraindication for hematopoietic stem cell transplantation (HSCT). Approximately 30% of transplants from related donors and up to 50% of transplants from unrelated donors are ABO incompatible. Immuno-hematologic investigations allow to estimate donor/recipient ABO mismatch and anti-A/B …
Aprende másTrue Donor Cell Leukemia after Allogeneic Hematopoietic Stem Cell ...
Donor cell leukemia (DCL) is a rare complication after allogeneic hematopoietic stem cell transplantation (HSCT) accounting for 0.1% of relapses and presenting as secondary leukemia of donor origin. Distinct in phenotype and cytogenetics from the original leukemia, DCL''s clinical challenge lies in its late onset. Its origin is …
Aprende másBrown adipose tissue transplantation improves whole-body energy ...
In the current study, we found that BAT transplantation improved whole-body energy metabolism and increased insulin sensitivity. In addition, BAT …
Aprende másProtein Kinase C-δ Mediates Kidney Tubular Injury in Cold Storage ...
In this study, we have demonstrated: (1) PKCδ is rapidly activated in renal tubular cells during cold-storage transplantation; (2) ... which involves intrinsic tubular cell proliferation for replacement of the lost tubular epithelium. 5, 54 Cell proliferation is an energy-requiring activity that depends on the activation of the cell cycle.
Aprende másNutritional recommendations in hematopoietic stem cell transplantation …
Protein requirements are also high and are generally met with the addition of 1.5–2 g/kg of body weight per day of a standard amino acid solution [22], [23] ( Table 2 ). Table 2. Nutritional requirements in hematopoietic stem cell transplantation. Nutrients. Severe malnutrition: severe complications.
Aprende másProtein blend ingestion before allogeneic stem cell transplantation ...
1. Introduction. Leukemia constitutes a group of malignant diseases of hematopoietic cells, including acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), that commonly occur in children and adolescents [1].A slowly increasing trend in leukemia-related mortality has been observed in China [2].Notably, severe …
Aprende másCell Transplantation
Stem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. ... Energy metabolism programming is a hallmark of cancer, and serves as a potent target of cancer therapy. ... The origins of low-temperature tissue storage research date back to the late 1800s. Over half a century later, osmotic ...
Aprende másComparison of pre
Patients undergoing hematopoietic stem cell transplantation may present with metabolic alterations that can have an effect on their energy expenditure and nutritional status. This project aimed to compare the pre- and posttransplant energy expenditures of patients undergoing hematopoietic stem cell transplantation as well as related factors.
Aprende másMON-P089: Resting Energy Expenditure in ONCO ...
DOI: 10.1016/S0261-5614(17)30994-9 Corpus ID: 80430680; MON-P089: Resting Energy Expenditure in ONCO-Hematological Patients During Hematopoietic Stem Cell Transplantation @article{Cmara2017MONP089RE, title={MON-P089: Resting Energy Expenditure in ONCO-Hematological Patients During Hematopoietic Stem Cell …
Aprende másImpact of hematopoietic stem cell transplantation in glycogen storage …
Hematopoietic stem cell transplantation / bone marrow transplantation (HSCT/BMT) is still considered in some patients with GSD Ib to correct neutropenia and avoid G-CSF related adverse effects. Whether HSCT also has an effect on the metabolic phenotype e.g., via improved and better intestinal utilization of carbohydrate sources, has …
Aprende másProtein blend ingestion before allogeneic stem cell transplantation ...
Our data showed that protein and energy intake decreased significantly (P < .05) after transplantation in both groups. In the absence of the BP intervention, dramatic decreases in muscle-related indicators (i.e., anthropometric variables, muscle strength and serum protein) were observed in the majority (>50%) of the patients.
Aprende másThe temperature-responsive hydroxybutyl chitosan hydrogels …
1. Introduction. Cell transplantation therapy, an interdisciplinary field that applied engineering and life science principles to promote regeneration, could potentially restore diseased and injured tissues and whole organs [1].Cell transplantation therapy has been applied to various tissue defects in heart, cornea, trachea, and cartilage.
Aprende másPreservation media, durations and cell concentrations of short …
Dextrose provides a source of energy for cell metabolism (Anderson et al., 1992). ... There is no standard protocol for short-term storage of fresh cells before transplantation as well as no relatively comprehensive evaluation of cell quality after storage. Previous study reported that MSCs stored in saline or dextrose for more than 2 …
Aprende másIJMS | Free Full-Text | Stem Cell Transplantation and Cell-Free …
Increasing attention has been paid to cell-based medicines. Many in vivo and in vitro studies have demonstrated the efficacy of stem cell transplantation for the regeneration of periodontal tissues over the past 20 years. Although positive evidence has accumulated regarding periodontal regeneration using stem cells, the exact mechanism …
Aprende másDuration of in vitro storage affects the key stem cell features of human bone marrow-derived mesenchymal stromal cells for clinical transplantation
After storage at 5 × 10 5 cells/mL for 1 h, 2 h, 4 h, 6 h or 8 h at 4 C or RT in 0.9% saline solution or 5% dextrose solution, cell viability was measured by Annexin V-FITC/propidium iodide staining. Cell viability decreased gradually when …
Aprende másProlonged hypothermic cardiac storage for transplantation
Prolonged hypothermic cardiac storage for transplantation The effects on myocardial metabolism and mitochondrial function Cardiac storage for transplantation is currently limited to 6 hours. ... total degradation products. after 12 hours and 18 ± 7 ~mol/gm after 24 hours of cold storage. The energy change decreased (p < …
Aprende másMitochondrial transfer/transplantation: an emerging ...
Multiple research groups have developed artificial mitochondrial transfer/transplantation (AMT/T) methods that transfer healthy mitochondria into …
Aprende másBiomaterial-Based Schwann Cell Transplantation and Schwann Cell …
Cell transplantation is considered to potentially ameliorate the injured environment in CNI treatments. The SCs and SC-like cells are the most promising cell lineages for cell-based therapies. ... and energy storage of living organisms in animals and plants. For example, hyaluronic acid (HA) is a linear, highly hydrated, non-sulfated …
Aprende másEnergy expenditure in children undergoing hematopoietic stem cell transplantation | Bone Marrow Transplantation
Prior studies suggest that patients undergoing hematopoietic stem cell transplantation (HSCT) for malignancy have nutritional needs that are greater than their estimated needs. To determine ...
Aprende másHepatocyte transplantation: The progress and the challenges
Numerous studies have shown that hepatocyte transplantation is a promising approach for liver diseases, such as liver-based metabolic diseases and acute liver failure. However, it lacks strong evidence to support the long-term therapeutic effects of hepatocyte transplantation in clinical practice. Currently, major hurdles include …
Aprende másThe emerging role of nanotechnology in cell and organ transplantation
Grand challenges in transplantation. Over the past two decades, through improved surgical procedures and the use of powerful immunosuppressive drugs, cell and organ (i.e., kidney, heart, liver, pancreas) transplantations have become the standard of care for millions of patients with end stage organ failure [1–4].Unfortunately, organ shortages, graft failure, …
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